Linerase Collagen is a high-purity, sterile, and pyrogen-free Type I Heterologous Collagen (HTIC) powder sourced from equine tissue. Designed as an injectable medical device, it is intended for dermal biorevitalization, supporting skin regeneration and structural repair. The product is reconstituted with 0.9% sodium chloride (normal saline) prior to administration.
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Linerase Collagen is a medical device containing Heterologous Type I Collagen (HTIC) derived from equine (horse) tendon, specifically designed to stimulate fibroblast activity and promote natural collagen regeneration in the skin. It is used primarily in aesthetic medicine to improve skin tone, elasticity, and volume through a biostimulating process.
Linerase is an injectable biorevitalization treatment that utilizes Type I collagen—the most abundant collagen in the human body—to stimulate dermal fibroblasts. This leads to the natural production of new collagen fibers, which enhances skin structure and firmness over time. It is used in aesthetic medicine to treat skin laxity, scarring, and signs of aging such as wrinkles and volume loss.
Each vial contains:
100 mg of lyophilized Heterologous Type I Collagen, derived from equine (horse) tendon
Reconstituted with 5 mL of 0.9% sodium chloride (saline) before use
It is sterile and pyrogen-free, ensuring safety and suitability for intradermal injection.
Linerase works by stimulating fibroblast activity in the skin. When injected, the Type I collagen molecules serve as a scaffold for new tissue regeneration. Fibroblasts are activated to produce native collagen, elastin, and other extracellular matrix components, thereby:
Enhancing dermal density
Improving skin elasticity
Supporting natural tissue remodeling
This mechanism leads to long-term skin rejuvenation without altering facial expressions or adding volume artificially.
The product is administered via intradermal injection using a fine 30G or 32G needle. It is reconstituted with 5 mL of 0.9% saline solution to form a smooth injectable mixture. Injections are typically spaced about 2 cm apart and administered across the treatment area.
This procedure should only be performed by licensed healthcare professionals trained in aesthetic medicine.
A standard treatment course consists of:
Four sessions, spaced two weeks apart
Maintenance treatments every 2–3 months, depending on individual needs
Treatment areas include the face, neck, décolleté, inner arms, thighs, and abdomen. Results are cumulative and typically visible after the second session.
Stimulates natural collagen production
Improves skin elasticity and tone
Reduces fine lines, wrinkles, and sagging
Enhances skin hydration and brightness
Aids in scar and stretch mark treatment
Suitable for both men and women
Non-volumizing and expression-preserving
Pricing may vary depending on the clinic, practitioner, and region. One vial of Linerase is typically used per treatment session. For accurate pricing and treatment planning, please contact a certified medical provider or clinic that offers Linerase.
Linerase Collagen should not be used in the following cases:
Hypersensitivity or allergy to collagen or equine-derived proteins
Pregnancy or breastfeeding
Presence of active skin infections, inflammation, or dermatologic conditions in the treatment area
Autoimmune or connective tissue disorders
Use in individuals under 18 years of age
Always consult a qualified healthcare professional before beginning treatment.
Linerase represents a scientific approach to skin rejuvenation—reviving your skin’s youthful structure by restoring what time has diminished. With consistent treatments guided by trained professionals, Linerase can help you achieve natural, long-lasting beauty by working with your body—not against it.
Experience aesthetic regeneration with a safe, clinically proven solution trusted by dermatologists and cosmetic doctors worldwide.